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Unioto suffered its first loss at the hands of Amanda Friday night, despite causing four turnovers.
The Panthers improved to 2-0 Friday with a blowout win over Vinton County.
In a Week 2 matchup, Wellston doubled up Piketon to win its first game this season.
Chillicothe earned its first win this season with a 13-point decision over Mifflin, Friday night.